Thibault Mésplède

Characterization of the R263K Mutation in HIV-1 Integrase That Confers Low-Level Resistance to the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir

Peter K. Quashie, Thibault Mésplède, Ying-Shan Han et al. · Journal of Virology · 2011 · 235 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation

Peyman Nakhaei, Thibault Mésplède, Mayra Solis et al. · PLoS Pathogens · 2009 · 171 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

Thibault Mésplède, Peter K. Quashie, Nathan Osman et al. · Retrovirology · 2013 · 132 citations · Full text

Life Sciences, Infectious Diseases, Pharmacotherapy +17

Selective resistance profiles emerging in patient-derived clinical isolates with cabotegravir, bictegravir, dolutegravir, and elvitegravir

Maureen Oliveira, Ruxandra-Ilinca Ibanescu, Kaitlin Anstett et al. · Retrovirology · 2018 · 118 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17

p53 Degradation Activity, Expression, and Subcellular Localization of E6 Proteins from 29 Human Papillomavirus Genotypes

Thibault Mésplède, David Gagnon, Fanny Bergeron-Labrecque et al. · Journal of Virology · 2011 · 95 citations · Full text

Life Sciences, Molecular Biology, Oncology +15