Ian Pyrah

Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats

Scott L. Taylor, Michael S. Ominsky, Rong Hu et al. · Bone · 2015 · 106 citations · Full text

Medicine, Orthopedic Surgery, Bone Augmentation +16

Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys

Michael S. Ominsky, Steven K. Boyd, Aurore Varela et al. · Journal of Bone and Mineral Research · 2016 · 103 citations · Full text

Medicine, Endocrinology, Bone Augmentation +16

Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody

Paul J. Kostenuik, Susan Y. Smith, Jacquelin Jolette et al. · Bone · 2011 · 100 citations

Medicine, Orthopedic Surgery, Bone Metabolism +15

Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys

Michael S. Ominsky, Brian Stouch, Joseph A. Schroeder et al. · Bone · 2011 · 98 citations

Medicine, Endocrinology, Immunology +17

Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats

Michael S. Ominsky, Danielle L. Brown, Gwyneth Van et al. · Bone · 2015 · 92 citations · Full text

Medicine, Endocrinology, Pharmacology +17