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Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys

Human Rankl AntibodyBone Turnover MarkersSclerostinOvariectomized Cynomolgus MonkeysImmunologyOsteoarthritisGynecologyBone MetabolismEndocrinologyMedicineOsteoporosisOrthopaedic Surgery