K.‐Y. LIN

Synthesis and binding properties of pyrimidine oligodeoxynucleoside analogs containing neutral phosphodiester replacements: the formacetal and 3'-thioformacetal internucleoside linkages

Robert J. Jones, K.‐Y. LIN, John F. Milligan et al. · The Journal of Organic Chemistry · 1993 · 96 citations

Pharmacy, Chemistry, Bioisosterism +16

Deoxyoligonucleotides bearing neutral analogs of phosphodiester linkages recognize duplex DNA via triple-helix formation

Mark Matteucci, K.‐Y. LIN, Samuel Butcher et al. · Journal of the American Chemical Society · 1991 · 49 citations

Life Sciences, Biology, Molecular Biology +13

Probing structural factors stabilizing antisense oligonucleotide duplexes: NMR studies of a DNA.cntdot.DNA duplex containing a formacetal linkage

Xiaolian Gao, Frank K. Brown, Peter W. Jeffs et al. · Biochemistry · 1992 · 34 citations

Life Sciences, Biology, Molecular Biology +16

Addition of glycinate enolate equivalents to 1,4-benzodiazepine imino phosphates. Preparation of synthetically useful 2-(ethyl glycinat-.alpha.-ylidene)-1,4-benzodiazepines and related derivatives

R. Ian Fryer, Linas V. Kudzma, Zi Qiang Gu et al. · The Journal of Organic Chemistry · 1991 · 14 citations

Pharmacy, Medicinal Chemistry, Pharmacology +5