Kenji Murano

Rational Approaches to Discovery of Orally Active and Brain-Penetrable Quinazolinone Inhibitors of Poly(ADP-ribose)polymerase

Kouji Hattori, Yoshiyuki Kido, Hirofumi Yamamoto et al. · Journal of Medicinal Chemistry · 2004 · 95 citations · Full text

Drug Target, Bioorganic Chemistry, Orally Active +18

Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling

Junya Ishida, Hirofumi Yamamoto, Yoshiyuki Kido et al. · Bioorganic & Medicinal Chemistry · 2005 · 82 citations · Full text

Molecular Docking, Sbdd Analysis, Medicinal Chemistry +12

Discovery of quinazolinone and quinoxaline derivatives as potent and selective poly(ADP‐ribose) polymerase‐1/2 inhibitors

Akinori Iwashita, Kouji Hattori, Hirofumi Yamamoto et al. · FEBS Letters · 2005 · 75 citations

Pharmaceutical Science, Bioorganic Chemistry, Quinoxaline Derivatives +18

Flavin-catalyzed aerobic oxidation of sulfides and thiols with formic acid/triethylamine

Shun‐Ichi Murahashi, Dazhi Zhang, Hiroki Iida et al. · Chemical Communications · 2014 · 63 citations

Chemical Engineering, Engineering, Formic Acid/tea +11

Synthesis and SAR of novel parenteral anti-pseudomonal cephalosporins: Discovery of FR264205

Ayako Toda, Hidenori Ohki, Toshio Yamanaka et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 55 citations

Medicinal Chemistry, Antimicrobial Drug Discovery, Bioorganic Chemistry +9