Stereoselective Synthesis of 2-Alkenylaziridines and 2-Alkenylazetidines by Palladium-Catalyzed Intramolecular Amination of α- and β-Amino Allenes

Hiroaki Ohno, Miyuki Anzai, Ayako Toda, +5

The Journal of Organic Chemistry

Enantioselective SynthesisEngineeringPalladium-catalyzed Cyclization ConditionsPalladium-catalyzed Intramolecular AminationOrganic Chemistry +10

First Palladium-Catalyzed Aziridination Reaction of Amino Allenes

Hiroaki Ohno, Ayako Toda, Yoshihisa Miwa, +5

The Journal of Organic Chemistry

Medicinal ChemistryCross-coupling ReactionEngineeringBiochemistryNatural Sciences +9

Synthesis and SAR of novel parenteral anti-pseudomonal cephalosporins: Discovery of FR264205

Ayako Toda, Hidenori Ohki, Toshio Yamanaka, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryAntimicrobial Drug DiscoveryBioorganic ChemistryMedicineNatural Sciences +7

Stereoselective Synthesis of Chiral Amino Allenes by Organocopper-Mediated anti-SN2′-Substitution Reaction of Chiral Ethynylaziridines

Hiroaki Ohno, Ayako Toda, Nobutaka Fujii, +3

Tetrahedron

EngineeringNatural SciencesDiversity-oriented SynthesisChiral EthynylaziridinesOrganic Chemistry +7

Synthesis of Allenes from Allylic Alcohol Derivatives Bearing a Bromine Atom Using a Palladium(0)/Diethylzinc System

Hiroaki Ohno, Kumiko Miyamura, Tetsuaki Tanaka, +5

The Journal of Organic Chemistry

Asymmetric CatalysisCross-coupling ReactionEngineeringAlkene MetathesisOrganic Chemistry +10

Structural requirements for the stability of novel cephalosporins to AmpC β-lactamase based on 3D-structure

Kenji Murano, Toshio Yamanaka, Ayako Toda, +10

Bioorganic & Medicinal Chemistry

EngineeringProtein AssemblyBiochemistryStructural RequirementsNovel Cephalosporins +9

Palladium-catalyzed regio- and stereoselective synthesis of N-protected 2,4-dialkylated azacyclobutanes from amino allenes

Miyuki Anzai, Ayako Toda, Hiroaki Ohno, +3

Tetrahedron Letters

EngineeringAmino AllenesOrganic ChemistryStereoselective SynthesisChemistry +4

Reactions of <i>N</i>-Arylsulfonyl-2,3-<i>cis</i>- and <i>N</i>-Arylsulfonyl-2,3-<i>trans</i>-3-alkyl-2-vinylaziridines with Organocopper Reagents:  Importance of 2,3-<i>cis</i>-Stereochemistry in Controlling Regio- and Stereoselectivity

Ayako Toda, Hiroshi Aoyama, Norio Mimura, +3

The Journal of Organic Chemistry

Cross-coupling ReactionEngineeringAlkene MetathesisBiochemistryCorresponding 2,3-Cis-isomers +9

Synthesis of chiral amino allenes via an organocyanocuprate-mediated ring-opening reaction of enantiopure ethynylaziridines

Hiroaki Ohno, Ayako Toda, Yoshihisa Miwa, +3

Tetrahedron Letters

Asymmetric CatalysisEngineeringOrganic ChemistryChiral Amino AllenesChemistry +5

Convenient syntheses of chiral 3-substituted 2-ethynylaziridines

Hiroaki Ohno, Ayako Toda, Yoshiji Takemoto, +2

Journal of the Chemical Society Perkin Transactions 1

Natural α-Amino AcidsDerivativesEngineeringConvenient SynthesesNatural Sciences +12