Tin‐Wein Yu

Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699

Paul R. August, Li Tang, Yeo Joon Yoon et al. · Chemistry & Biology · 1998 · 350 citations · Full text

Life Sciences, Microbiology, Molecular Biology +8

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from <i>Actinosynnema</i> <i>pretiosum</i>

Tin‐Wein Yu, Linquan Bai, Dorothee Clade et al. · Proceedings of the National Academy of Sciences · 2002 · 286 citations · Full text

Life Sciences, Biochemistry, Microbiology +15

Direct evidence that the rifamycin polyketide synthase assembles polyketide chains processively

Tin‐Wein Yu, Yuemao Shen, Y. Doi-Katayama et al. · Proceedings of the National Academy of Sciences · 1999 · 138 citations

Life Sciences, Biochemistry, Molecular Biology +12

3-Amino-5-hydroxybenzoic Acid Synthase, the Terminal Enzyme in the Formation of the Precursor of mC7N Units in Rifamycin and Related Antibiotics

Chun-Gyu Kim, Tin‐Wein Yu, Craig B. Fryhle et al. · Journal of Biological Chemistry · 1998 · 113 citations · Full text

Life Sciences, Biochemistry, Microbiology +13

Mutational Analysis and Reconstituted Expression of the Biosynthetic Genes Involved in the Formation of 3-Amino-5-hydroxybenzoic Acid, the Starter Unit of Rifamycin Biosynthesis in Amycolatopsis mediterraneiS699

Tin‐Wein Yu, Rolf Müller, Michael Müller et al. · Journal of Biological Chemistry · 2001 · 93 citations · Full text

Life Sciences, Biochemistry, Microbiology +11