Andrew A. Godfrey

Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

Andrew Barker, Keith H. Gibson, Walter Grundy et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 559 citations · Full text

Molecular Pharmacology, Drug Targeting, Oncology +10

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced p<i>K</i>_a: Antibacterial Agents with an Improved Safety Profile

Folkert Reck, Richard A. Alm, Patrick Brassil et al. · Journal of Medicinal Chemistry · 2012 · 88 citations · Full text

Epidermal growth factor receptor tyrosine kinase: Structure-activity relationships and antitumour activity of novel quinazolines

Keith H. Gibson, Walter Grundy, Andrew A. Godfrey et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 55 citations

Signaling Pathway, Medicine, Receptor Tyrosine Kinase +9

The Preparation of (−)-Grandisine B from (+)-Grandisine D; A Biomimetic Total Synthesis or Formation of an Isolation Artefact?

James D. Cuthbertson, Andrew A. Godfrey, Richard J. K. Taylor · Organic Letters · 2011 · 29 citations

Diversity Oriented Synthesis, Enantioselective Synthesis, Engineering +14

Synthesis of isoquinuclidinones via a tandem amination/imination sequence: application to the synthesis of (−)-mearsine

James D. Cuthbertson, Andrew A. Godfrey, Richard J. K. Taylor · Tetrahedron Letters · 2010 · 15 citations

Tandem Amination/imination Sequence, Engineering, Diversity-oriented Synthesis +5