Andrew A. Godfrey

Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

Andrew Barker, Keith H. Gibson, Walter Grundy et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 563 citations · Full text

Medicine, Oncology, Pharmacology +9

Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II with Reduced p<i>K</i>_a: Antibacterial Agents with an Improved Safety Profile

Folkert Reck, Richard A. Alm, Patrick Brassil et al. · Journal of Medicinal Chemistry · 2012 · 92 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Epidermal growth factor receptor tyrosine kinase: Structure-activity relationships and antitumour activity of novel quinazolines

Keith H. Gibson, Walter Grundy, Andrew A. Godfrey et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 55 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

The Preparation of (−)-Grandisine B from (+)-Grandisine D; A Biomimetic Total Synthesis or Formation of an Isolation Artefact?

James D. Cuthbertson, Andrew A. Godfrey, Richard J. K. Taylor · Organic Letters · 2011 · 29 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Synthesis of isoquinuclidinones via a tandem amination/imination sequence: application to the synthesis of (−)-mearsine

James D. Cuthbertson, Andrew A. Godfrey, Richard J. K. Taylor · Tetrahedron Letters · 2010 · 15 citations

Natural Sciences, Chemistry, Medicinal Chemistry +6