Andrew Barker

Studies leading to the identification of ZD1839 (iressa™): an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor targeted to the treatment of cancer

Andrew Barker, Keith H. Gibson, Walter Grundy et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 559 citations · Full text

Molecular Pharmacology, Drug Targeting, Oncology +10

miR-331-3p Regulates ERBB-2 Expression and Androgen Receptor Signaling in Prostate Cancer

Michael R. Epis, Keith M. Giles, Andrew Barker et al. · Journal of Biological Chemistry · 2009 · 162 citations · Full text

Erbb-2 Expression, Androgen Receptor, Transcriptional Regulation +14

Four dimers of λ repressor bound to two suitably spaced pairs of λ operators form octamers and DNA loops over large distances

Bernard Révet, B. von Wilcken‐Bergmann, Heike Bessert et al. · Current Biology · 1999 · 132 citations · Full text

Spectral Theory, λ Repressor Bound, Large Distances +1

SLIRP, a Small SRA Binding Protein, Is a Nuclear Receptor Corepressor

Esme C. Hatchell, Shane M. Colley, Dianne J. Beveridge et al. · Molecular Cell · 2006 · 130 citations · Full text

Protein Function, Signal Transduction, Nuclear Receptor Corepressor +6

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

Andrew Redfern, Shane M. Colley, Dianne J. Beveridge et al. · Proceedings of the National Academy of Sciences · 2013 · 127 citations · Full text

Engineering, Estrogen Receptor, Molecular Biology +23