Lihe Lu

Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

Yuanzhi Ye, An Chen, Li Li et al. · Kidney International · 2022 · 358 citations

Life Sciences, Cell Biology, Physiology +16

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals

Xiuli Zhang, Yining Li, Pingzhen Yang et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2020 · 275 citations · Full text

Life Sciences, Biochemistry, Nephrology +15

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure

Lihe Lu, WU Wei-kang, Jianyun Yan et al. · International Journal of Cardiology · 2008 · 175 citations

Life Sciences, Cardiology, Cell Biology +16

Ghrelin prevents doxorubicin-induced cardiotoxicity through TNF-alpha/NF-κB pathways and mitochondrial protective mechanisms

Zhiwei Xu, Shiqing Lin, Wei-Kang Wu et al. · Toxicology · 2008 · 116 citations

Life Sciences, Cell Biology, Pharmacology +16

Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway

Xiaoyu Liu, An Chen, Qingchun Liang et al. · Aging Cell · 2021 · 102 citations · Full text

Medicine, Molecular Medicine, Nephrology +13