An Chen

Repression of the antiporter SLC7A11/glutathione/glutathione peroxidase 4 axis drives ferroptosis of vascular smooth muscle cells to facilitate vascular calcification

Yuanzhi Ye, An Chen, Li Li et al. · Kidney International · 2022 · 325 citations

Molecular Physiology, Axis Drives Ferroptosis, Biochemistry +13

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

Jinping Zhang, Sang‐Myeong Lee, Stephen Shannon et al. · Journal of Clinical Investigation · 2009 · 282 citations · Full text

Histone Modifications, Sirt1 Function, Epigenetic Change +20

Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis

Quan Qiu, Ze Zheng, Lin Chang et al. · The EMBO Journal · 2013 · 213 citations · Full text

Plasma proteome of severe acute respiratory syndrome analyzed by two-dimensional gel electrophoresis and mass spectrometry

Jenn‐Han Chen, Yu‐Wang Chang, Chen‐Wen Yao et al. · Proceedings of the National Academy of Sciences · 2004 · 117 citations · Full text

Serial Cascades, Immunology, Pathology +22

Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen‐induced arthritis

Beixue Gao, Sang‐Myeong Lee, An Chen et al. · EMBO Reports · 2008 · 114 citations · Full text

Inflammation, Rheumatology, Musculoskeletal Research +14