Martine Michiels

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 1. Synthesis and Structure−Activity Relationship of a Class of Human Immunodeficiency Virus type 1 Integrase Inhibitors

Serena Pasquini, Claudia Mugnaini, Cristina Tintori et al. · Journal of Medicinal Chemistry · 2008 · 164 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +17

Upscaling of lentiviral vector production by tangential flow filtration

Martine Geraerts, Martine Michiels, Veerle Baekelandt et al. · The Journal of Gene Medicine · 2005 · 157 citations · Full text

Life Sciences, Bioengineering, Biotechnology +14

Development of Resistance against Diketo Derivatives of Human Immunodeficiency Virus Type 1 by Progressive Accumulation of Integrase Mutations

Valery Fikkert, Bénédicte Van Maele, Jo Vercammen et al. · Journal of Virology · 2003 · 98 citations · Full text

Life Sciences, Medicinal Chemistry, Drug Discovery +12

A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series

Laura De Luca, Maria Letizia Barreca, Stefania Ferro et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 33 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Preclinical Evaluation of 1H-Benzylindole Derivatives as Novel Human Immunodeficiency Virus Integrase Strand Transfer Inhibitors

Anneleen Hombrouck, Barbara Van Remoortel, Martine Michiels et al. · Antimicrobial Agents and Chemotherapy · 2008 · 19 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17