Ruth Witt

Next-generation personalised medicine for high-risk paediatric cancer patients – The INFORM pilot study

Barbara C. Worst, Cornelis M. van Tilburg, Gnana Prakash Balasubramanian et al. · European Journal of Cancer · 2016 · 336 citations · Full text

Medicine, Oncology, Pediatrics +11

The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets

Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler et al. · Cancer Discovery · 2021 · 260 citations · Full text

Medicine, Oncology, Pediatrics +13

Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience

Elke Pfaff, Ahmed El Damaty, Gnana Prakash Balasubramanian et al. · European Journal of Cancer · 2019 · 85 citations

Medicine, Oncology, Pediatrics +15

LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration

Cornelis M. van Tilburg, Lindsay Kilburn, Sébastien Perreault et al. · BMC Cancer · 2024 · 59 citations · Full text

Medicine, Oncology, Pharmacology +14

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

Cornelis M. van Tilburg, Till Milde, Ruth Witt et al. · Clinical Epigenetics · 2019 · 44 citations · Full text

Medicine, Oncology, Pharmacology +17