Elke Pfaff

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.6K citations

Chromatin, Neuro-oncology, Chromatin Structure +13

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.8K citations · Full text

Neuro-oncology, Radiation Oncology, Somatic Variant +11

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Dominik Sturm, Brent A. Orr, Umut H. Toprak et al. · Cell · 2016 · 973 citations · Full text

Neuro-oncology, Molecular Classification, Cerebral Organoid +8

Dissecting the genomic complexity underlying medulloblastoma

David Jones, Natalie Jäger, Marcel Kool et al. · Nature · 2012 · 870 citations · Full text

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

Tobias Rausch, David Jones, Marc Zapatka et al. · Cell · 2012 · 857 citations · Full text

Dna Sequencing, Somatic Variant, Tumor Heterogeneity +8