Zhixiang Yang

γ-Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer’s Disease

Lutgarde Serneels, Jérôme Van Biervliet, Katleen Craessaerts et al. · Science · 2009 · 256 citations · Full text

Protein Secretion, Molecular Biology, Neurochemical Biomarkers +19

The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central Aβ Pharmacodynamic Responses in Mice, Dogs, and Humans

Patrick C. May, Brian A. Willis, Stephen L. Lowe et al. · Journal of Neuroscience · 2015 · 195 citations · Full text

Amyloid β, Neurodegenerative Diseases, Amyloid Lowering +15

Clinical study of recombinant adenovirus-p53 combined with fractionated stereotactic radiotherapy for hepatocellular carcinoma

Zhixiang Yang, Dong Wang, Ge Wang et al. · Journal of Cancer Research and Clinical Oncology · 2009 · 85 citations · Full text

Surgical Oncology, Hepatology, Radiation Therapy +11

Identification of novel proteolytically inactive mutations in coronavirus 3C‐like protease using a combined approach

Liurong Fang, Zhixiang Yang, Shangen Xu et al. · The FASEB Journal · 2019 · 60 citations

O3-06-07 Multi-compartmental pharmacodynamic assessment of the functional gamma-secretase inhibitor LY450139 in PDAPP transgenic mice and non-transgenic mice

Patrick C. May, Zhixiang Yang, Weiying Li et al. · Neurobiology of Aging · 2004 · 38 citations

Knockout Mouse, Molecular Pharmacology, Translational Pharmacology +7