M. R. HARNDEN

Selection of an oral prodrug (BRL 42810; famciclovir) for the antiherpesvirus agent BRL 39123 [9-(4-hydroxy-3-hydroxymethylbut-l-yl)guanine; penciclovir]

R. Anthony Vere Hodge, David Sutton, M R Boyd et al. · Antimicrobial Agents and Chemotherapy · 1989 · 210 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

An improved synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine

M. R. HARNDEN, Richard L. Jarvest · Tetrahedron Letters · 1985 · 55 citations

Pharmacy, Medicinal Chemistry, Molecular Virology +8

Synthesis and antiviral activity of 9-alkoxypurines. 2. 9-(2,3-Dihydroxypropoxy)-, 9-(3,4-dihydroxybutoxy)-, and 9-(1,4-dihydroxybut-2-oxy)purines

Stuart Bailey, M. R. HARNDEN, Richard L. Jarvest et al. · Journal of Medicinal Chemistry · 1991 · 35 citations

Medicine, Medicinal Chemistry, Pharmacology +8

C nucleoside studies part 21 synthesis of some hydroxyalkylated pyrrolo 3 2 d pyrimidines and thieno 3 2 d pyrimidines related to known antiviral acyclonucleosides

J. G. Buchanan, David Craven, R. H. WIGHTMAN et al. · Journal of The Chemical Society-perkin Transactions 1 · 1991 · 30 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Synthesis of 9-(3-hydroxypropoxy)guanine, a novel antiviral acyclonucleoside

M. R. HARNDEN, Amy Parkin, Paul G. Wyatt · Tetrahedron Letters · 1988 · 23 citations

Pharmacy, Medicinal Chemistry, Molecular Virology +7