Bryan Kramer

Lead optimization of 4-(dimethylamino)quinazolines, potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1

Kosuke Kanuma, Katsunori Omodera, Mariko Nishiguchi et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 28 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Discovery of 2-(((1<i>r</i>,4<i>r</i>)-4-(((4-Chlorophenyl)(phenyl)carbamoyl)oxy)methyl)cyclohexyl)methoxy)acetate (Ralinepag): An Orally Active Prostacyclin Receptor Agonist for the Treatment of Pulmonary Arterial Hypertension

Thuy-Anh Tran, Bryan Kramer, Young‐Jun Shin et al. · Journal of Medicinal Chemistry · 2017 · 17 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15