Joana R. F. Abreu

Simultaneous Detection of Circulating Autoreactive CD8+ T-Cells Specific for Different Islet Cell–Associated Epitopes Using Combinatorial MHC Multimers

J. Velthuis, Wendy W. J. Unger, Joana R. F. Abreu et al. · Diabetes · 2010 · 202 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Plasmid-Encoded Proinsulin Preserves C-Peptide While Specifically Reducing Proinsulin-Specific CD8 ⁺ T Cells in Type 1 Diabetes

Bart O. Roep, Nanette Solvason, Peter A. Gottlieb et al. · Science Translational Medicine · 2013 · 166 citations · Full text

Life Sciences, Immunology, Molecular Biology +13

Immunological Balance Is Associated with Clinical Outcome after Autologous Hematopoietic Stem Cell Transplantation in Type 1 Diabetes

Kelen Cristina Ribeiro Malmegrim, Júlia Teixeira Cottas de Azevedo, Lucas C. M. Arruda et al. · Frontiers in Immunology · 2017 · 118 citations · Full text

Life Sciences, Endocrinology, Immunology +16

Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

Wendy W. J. Unger, Todd Pearson, Joana R. F. Abreu et al. · PLoS ONE · 2012 · 69 citations · Full text

Life Sciences, Endocrinology, Immunology +17

Discovery of low-affinity preproinsulin epitopes and detection of autoreactive CD8 T-cells using combinatorial MHC multimers

Wendy W. J. Unger, J. Velthuis, Joana R. F. Abreu et al. · Journal of Autoimmunity · 2011 · 58 citations

Life Sciences, Immunology, Molecular Biology +16