K H Cowan

Glutathione S-transferases and drug resistance

Charles S. Morrow, K H Cowan · International Journal of Biochemistry · 1991 · 305 citations

Life Sciences, Biochemistry, Pharmacology +12

Elevation of pi class glutathione S-transferase activity in human breast cancer cells by transfection of the GST pi gene and its effect on sensitivity to toxins.

Jeffrey A. Moscow, Alan J. Townsend, K H Cowan · Molecular Pharmacology · 1989 · 172 citations

Life Sciences, Biochemistry, Molecular Biology +13

Paclitaxel chemotherapy after autologous stem-cell transplantation and engraftment of hematopoietic cells transduced with a retrovirus containing the multidrug resistance complementary DNA (MDR1) in metastatic breast cancer patients.

K H Cowan, Jeffrey A. Moscow, Hui Huang et al. · PubMed · 1999 · 125 citations

Medicine, Oncology, Pharmacology +17

Biochemical correlates of the antitumor and antimitochondrial properties of gossypol enantiomers.

Christopher C. Benz, Max A. Keniry, James M. Ford et al. · Molecular Pharmacology · 1990 · 112 citations

Medicine, Oncology, Pharmacology +15

Differences in phosphate metabolite levels in drug-sensitive and -resistant human breast cancer cell lines determined by 31P magnetic resonance spectroscopy.

Jack S. Cohen, Robbe C. Lyon, C. Chen et al. · PubMed · 1986 · 100 citations

Life Sciences, Biochemistry, Pharmacology +17