Sam Heywood

Prolonged in Vivo Residence Times of Antibody Fragments Associated with Albumin

Bryan John Smith, Andrew G. Popplewell, Dee Athwal et al. · Bioconjugate Chemistry · 2001 · 92 citations

Extending the half-life of a fab fragment through generation of a humanized anti-human serum albumin Fv domain: An investigation into the correlation between affinity and serum half-life

Ralph Adams, Laura Griffin, Joanne Compson et al. · mAbs · 2016 · 64 citations · Full text

Crystal Structure, Immunology, Molecular Biology +17

Alternative antibody Fab′ fragment PEGylation strategies: combination of strong reducing agents, disruption of the interchain disulphide bond and disulphide engineering

David P. Humphreys, Sam Heywood, Alistair J. Henry et al. · Protein Engineering Design and Selection · 2007 · 46 citations

Peg Size, Peptide Science, Chemical Biology +17

Cell surface dynamics and cellular distribution of endogenous FcRn

Lena E. D’Hooghe, Andrew D. Chalmers, Sam Heywood et al. · PLoS ONE · 2017 · 43 citations · Full text

Signal Transduction, Steady State, Cell Interaction +14

Towards a universal disulphide stabilised single chain Fv format: importance of interchain disulphide bond location and vL-vH orientation

Eve E. Weatherill, Katharine Cain, Sam Heywood et al. · Protein Engineering Design and Selection · 2012 · 42 citations