Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6.

T Tamura, Nobuyuki Udagawa, N. Takahashi, +7

Proceedings of the National Academy of Sciences

InflammationSil-6r InducesCytokineSclerostinBone Morphogenic Protein +12

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.

Toshimasa Tsujinaka, Junya Fujita, Chikara Ebisui, +8

Journal of Clinical Investigation

Muscle FunctionImmunologyImmune RegulationCell DeathMil-6r Antibody +23

Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

Masashi Narazaki, K Yasukawa, Takuro Saito, +6

Blood

Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130

Masashi Narazaki, K Yasukawa, Takuro Saito, +6

Blood

Blockade of interleukin‐6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury

Seiji Okada, Masaya Nakamura, Yuji Mikami, +8

Journal of Neuroscience Research

INTERLEUKIN-6 (IL-6) INDUCES THE PROLIFERATION OF SYNOVIAL FIBROBLASTIC CELLS IN THE PRESENCE OF SOLUBLE IL-6 RECEPTOR

Masahiko Mihara, Yoichiro Moriya, Tadamitsu Kishimoto, +1

Lara D. Veeken

InflammationRheumatologyCytokineRheumatoid DisorderAutoimmune Disease +13

Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis

Takeru Yoshimura, Koh‐Hei Sonoda, Nobuyuki Ohguro, +6

Lara D. Veeken

IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice

Masahiko Mihara, Nobuhiro Takagi, Yasuaki Takeda, +1

Clinical & Experimental Immunology

Muscle Undergoes Atrophy in Association with Increase of Lysosomal Cathepsin Activity in Interleukin-6 Transgenic Mouse

Toshimasa Tsujinaka, Chikara Ebisui, Junya Fujita, +7

Biochemical and Biophysical Research Communications

InflammationMuscle FunctionMolecular PhysiologyMuscle InjuryDisease Mechanism +12

Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(II) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody.

Yasuo Mizutani, Benjamin Bonavida, Yasuo Koishihara, +3

PubMed

ImmunologyPathologyCell DeathImmunotherapyHuman Rcc Cells +14