Elaine Cheng

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

Michael Krauthammer, Yong Kong, Byung Hak Ha et al. · Nature Genetics · 2012 · 1.2K citations

Medicine, Genetics, Oncology +12

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas

Michael Krauthammer, Yong Kong, Antonella Bacchiocchi et al. · Nature Genetics · 2015 · 405 citations

Medicine, Genetics, Molecular Genetics +16

PLX4032, a selective BRAF ^V600E kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF ^WT melanoma cells

Ruth Halaban, Wengeng Zhang, Antonella Bacchiocchi et al. · Pigment Cell & Melanoma Research · 2010 · 323 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Aberrant retention of tyrosinase in the endoplasmic reticulum mediates accelerated degradation of the enzyme and contributes to the dedifferentiated phenotype of amelanotic melanoma cells

Ruth Halaban, Elaine Cheng, Yuhua Zhang et al. · Proceedings of the National Academy of Sciences · 1997 · 259 citations

Life Sciences, Biochemistry, Oncology +17

Genome-wide screen of promoter methylation identifies novel markers in melanoma

Yasuo Koga, Mattia Pelizzola, Elaine Cheng et al. · Genome Research · 2009 · 203 citations · Full text

Life Sciences, Genetics, Molecular Biology +17