DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

J. Kirsty Millar, Ben Pickard, Shaun Mackie, +17

Science

Behavioral Phenotypes of Disc1 Missense Mutations in Mice

Steven J. Clapcote, Tatiana V. Lipina, J. Kirsty Millar, +15

Neuron

Knockout MouseDevelopmental BiologyGenetic DisorderGeneticsDegenerative Disease +2

Cytogenetics and infertility in man*

Ann C. Chandley, P Edmond, Sheila Christie, +4

Annals of Human Genetics

SpermatogenesisFertilityCytogeneticsGeneticsSemen Analysis +14

Yeast two-hybrid screens implicate DISC1 in brain development and function

J. Kirsty Millar, Sheila Christie, David J. Porteous

Biochemical and Biophysical Research Communications

Molecular NeuroscienceDevelopmental BiologyDevelopmental Cognitive NeuroscienceBrain DevelopmentCerebral Organoid +10

A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys–Drash syndrome

C.E. Patek, Melissa H. Little, Stewart Fleming, +11

Proceedings of the National Academy of Sciences

Chromosomal Location and Genomic Structure of the Human Translin-Associated Factor X Gene (TRAX; TSNAX) Revealed by Intergenic Splicing to DISC1, a Gene Disrupted by a Translocation Segregating with Schizophrenia

J. Kirsty Millar, Sheila Christie, Colin A. Semple, +1

Genomics

ChromatinChromosomal LocationGenetic DisorderGeneticsPsychiatric Genetics +7

Disrupted In Schizophrenia 1 (DISC1): Subcellular targeting and induction of ring mitochondria

J. Kirsty Millar, Rachel James, Sheila Christie, +1

Molecular and Cellular Neuroscience

Schizophrenia 1MedicineSchizophreniaDegenerative PathologyNeuroscience +5

DISC1, PDE4B, and NDE1 at the centrosome and synapse

Nicholas J. Bradshaw, Fumiaki Ogawa, Beatriz Antolin‐Fontes, +6

Biochemical and Biophysical Research Communications

CytoskeletonNeurotransmitterNeuroscienceMolecular Biology

Translocation heterozygosity and associated subfertility in man

Ann C. Chandley, Sheila Christie, Judith Fletcher, +2

Cytogenetic and Genome Research

SpermatogenesisTranslocation HeterozygosityFertilityCytogeneticsGenetics +18

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

Jennifer E. Eykelenboom, Gareth James Briggs, Nicholas J. Bradshaw, +15

Human Molecular Genetics

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsEpigenetics +26