Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

B Millauer, Laura K. Shawver, Karl H. Plate, +2

Nature

Tumor BiologyNeuro-oncologyGlioblastoma GrowthMedicineReceptor Tyrosine Kinase +9

Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells.

Robert M. Hudziak, Joseph Schlessinger, Axel Ullrich

Proceedings of the National Academy of Sciences

Breast OncologyExtensive HomologyCell ProliferationCancer BiologyTumor Biology +14

Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement

I-hsin Su, Ashwin Basavaraj, Andrew N. Krutchinsky, +4

Nature Immunology

Histone ModificationsChromatinDevelopmental BiologyIgh RearrangementChromatin Remodeling +10

HER-2/neu oncogene protein and prognosis in breast cancer.

Amol Tandon, Gary M. Clark, Gary C. Chamness, +2

Journal of Clinical Oncology

Gene AmplificationBreast OncologyOncogenic AgentMedicineImmunology +12

Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli

Jürgen Brosius, Axel Ullrich, Mary Alice Raker, +4

Plasmid

Recombinant PlasmidsE. ColiProtein BiosynthesisGeneticsGenetic Engineering +8

Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo.

B Millauer, M P Longhi, Karl H. Plate, +4

PubMed

PathologyCancer BiologyGliomaDominant-negative MethodologyTumor Biology +16

Flk-1 as a target for tumor growth inhibition.

L M Strawn, Gerald McMahon, Harald App, +15

PubMed

Endothelial CellsCancer BiologyTumor BiologyAngiogenesisReceptor Tyrosine Kinase +16

Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth.

Jay Sarup, R. M. Johnson, K. L. King, +5

PubMed

Breast OncologyImmunologyImmunotherapyCancer BiologyTumor Biology +16

Ligand activation of overexpressed epidermal growth factor receptors transforms NIH 3T3 mouse fibroblasts.

Heimo Riedel, S. Massoglia, Joseph Schlessinger, +1

Proceedings of the National Academy of Sciences

Cell ProliferationMouse FibroblastsCell GrowthNih 3T3Cell Surface Receptor +15

The human EGF receptor gene: structure of the 110 kb locus and identification of sequences regulating its transcription.

John D. Haley, Nigel Whittle, P Bennet, +3

PubMed

GeneticsCotransfection ExperimentsEpigeneticsTranscriptional RegulationProtein Expression +16