Regulation of the Fibrosis and Angiogenesis Promoter SPARC/Osteonectin in Human Adipose Tissue by Weight Change, Leptin, Insulin, and Glucose

Katarina Kos, Steve Wong, Bee K. Tan, +9

Diabetes

A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control

Vinay Bhaskar, Ira D. Goldfine, Daniel Bedinger, +19

Diabetes

Plasma obestatin levels are lower in obese and post-gastrectomy subjects, but do not change in response to a meal

M. S. B. Huda, Benjamin H. Durham, Steve Wong, +6

International Journal of Obesity

ObesityMetabolic SyndromeNutritionBariatric SurgerySleeve Gastrectomy +8

Ghrelin restores ‘lean-type’ hunger and energy expenditure profiles in morbidly obese subjects but has no effect on postgastrectomy subjects

M. S. B. Huda, Terence M. Dovey, Steve Wong, +8

International Journal of Obesity

ObesityNutritionBariatric SurgeryMetabolic SyndromeEnergy Expenditure Profiles +12

Adipokines and the insulin resistance syndrome in familial partial lipodystrophy caused by a mutation in lamin A/C

Steve Wong, M. S. B. Huda, Patrick English, +5

Diabetologia

ObesityMetabolic SyndromeMetabolic DisorderFamilial Partial LipodystrophyDiabetes +5

Human RBP4 adipose tissue expression is gender specific and influenced by leptin

Katarina Kos, Steve Wong, Bee K. Tan, +4

Clinical Endocrinology

Lack of an acute effect of ghrelin on markers of bone turnover in healthy controls and post-gastrectomy subjects

M. S. B. Huda, Benjamin H. Durham, Steve Wong, +6

Bone

Metabolic Bone DiseaseClinical NutritionGastroenterologyBone TurnoverHealthy Controls +6

Inhibition of insulin receptor function by a human, allosteric monoclonal antibody

John Corbin, Vinay Bhaskar, Ira D. Goldfine, +23

mAbs

ImmunologyInsulin ReceptorInsulin SignalingMetabolic SyndromeAntibody Engineering +15

Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity

John Corbin, Vinay Bhaskar, Ira D. Goldfine, +21

PLoS ONE

Insulin ReceptorGlucose ToleranceInsulin SignalingMetabolic SyndromeGlucose Metabolism +18

Ghrelin does not orchestrate the metabolic changes seen in fasting but has significant effects on lipid mobilisation and substrate utilisation

M. S. B. Huda, Terence M. Dovey, Steve Wong, +10

European Journal of Endocrinology