Advanced glycation end products increase retinal vascular endothelial growth factor expression.

Ming Y. Lu, Manabu Kuroki, Seiji Amano, +5

Journal of Clinical Investigation

Diabetic RetinopathyOcular DiseaseAngiogenesisDevelopmental BiologyOphthalmology +13

Pigment epithelium-derived factor prevents advanced glycation end products-induced monocyte chemoattractant protein-1 production in microvascular endothelial cells by suppressing intracellular reactive oxygen species generation

Yuji Inagaki, Sho‐ichi Yamagishi, T Okamoto, +2

Diabetologia

InflammationAngiogenesisImmunologyEndothelial DysfunctionVascular Biology +8

Bone Anabolic Effects of S-40503, a Novel Nonsteroidal Selective Androgen Receptor Modulator (SARM), in Rat Models of Osteoporosis

Keigo Hanada, Kazuyuki Furuya, Noriko Yamamoto, +7

Biological and Pharmaceutical Bulletin

Suppression of hypoxia-associated vascular endothelial growth factor gene expression by nitric oxide via cGMP.

Neil Ghiso, Richard M. Rohan, Seiji Amano, +2

PubMed

Total synthesis of paniculide A from d-glucose

Seiji Amano, Noriaki Takemura, Masami Ohtsuka, +2

Tetrahedron

BiosynthesisEngineeringBioorganic ChemistryTotal SynthesisPolysaccharide +3

Chiral and stereoselective total synthesis of novel immunosuppressant FR65814 from d-glucose

Seiji Amano, Noriko Ogawa, Masami Ohtsuka, +1

Tetrahedron

Medicinal ChemistryNovel Immunosuppressant Fr65814BiochemistryStereoselective Total SynthesisNatural Sciences +7

Serum levels of glucose-derived advanced glycation end products are associated with the severity of diabetic retinopathy in type 2 diabetic patients without renal dysfunction.

Kiyoshi Koga, Sho‐ichi Yamagishi, Taro Okamoto, +4

PubMed

AgingMetabolic SyndromeDiabetic RetinopathyLongevityChronic Kidney Disease +15

Angiotensin II-type 1 receptor interaction upregulates vascular endothelial growth factor messenger RNA levels in retinal pericytes through intracellular reactive oxygen species generation.

Sho Ichi Yamagishi, Seiji Amano, Yuji Inagaki, +6

PubMed

Retinal PericytesAng IiAngiotensin Ii-type 1Oxidative StressInflammation +19

5?-Nucleotidase activity in human astrocytomas

Seiji Amano, G. W. Kreutzberg, Martin Reddington

Acta Neuropathologica

Biochemistry-Nucleotidase ActivityNatural SciencesMolecular BiologyOrganelle Dynamic +1

Advanced Glycation End Products Increase Retinal Vascular Endothelial Growth Factor Expression.

Meng-Chuan Lu, Manabu Kuroki, Seiji Amano, +5

Retina

Romance StudiesLiterary HistoryOcular DiseaseOphthalmologyGlycobiology +8