A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics

Longlong Si, Haiqing Bai, Melissa Rodas, +35

Nature Biomedical Engineering

Viral DiagnosticsRapid IdentificationMedicineCandidate Antiviral TherapeuticsAntiviral Response +5

An extracorporeal blood-cleansing device for sepsis therapy

Joo H. Kang, Michael Super, Chong Wing Yung, +19

Nature Medicine

Sepsis TherapyMedicineSepsisSepsis PhenotypingLaboratory Medicine +1

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

Haiqing Bai, Longlong Si, Amanda Jiang, +12

Nature Communications

Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip

Amir Bein, Seong‐Min Kim, Girija Goyal, +20

Frontiers in Pharmacology

Treatment ModeledViral DiagnosticsImmunologyViral PathogenesisViral Dynamic +20

Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption

Tohid F. Didar, Mark Cartwright, Martin Rottman, +13

Biomaterials

Extracorporeal Opsonin HemoadsorptionSystemic Blood InfectionsAntibioticsHealthcare-associated InfectionHematology +4

Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics

Longlong Si, Haiqing Bai, Melissa Rodas, +29

EngineeringInflammatory Lung DiseaseViral DiagnosticsSynthetic VirologyViral Pathogenesis +20

Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles

Joo H. Kang, Eujin Um, Alexander J. Diaz, +7

Small

Discovery of influenza drug resistance mutations and host therapeutic targets using a human airway chip

Longlong Si, Rachelle Prantil‐Baun, Kambez H. Benam, +4

Drug TargetOrgan Chip ModelSynthetic VirologyImmunologyMolecular Biology +15

Mechanical control of innate immune responses against viral infection revealed in a human Lung Alveolus Chip

Haiqing Bai, Longlong Si, Amanda Jiang, +10

PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19

James Logue, Arup Chakraborty, Robert M. Johnson, +15

Communications Biology