Role of Proinflammatory Cytokines IL-18 and IL-1β in Bleomycin-Induced Lung Injury in Humans and Mice

Tomoaki Hoshino, Masaki Okamoto, Yuki Sakazaki, +3

American Journal of Respiratory Cell and Molecular Biology

Acute Lung InjuryInflammatory Lung DiseaseImmunotoxicologyLung InflammationBleomycin-induced Lung Injury +18

IL-38: A new factor in rheumatoid arthritis

Shinichi Takenaka, Shinjiro Kaieda, Tomotaka Kawayama, +11

Biochemistry and Biophysics Reports

IL-18 Induces Airway Hyperresponsiveness and Pulmonary Inflammation via CD4+ T Cell and IL-13

Masanori Sawada, Tomotaka Kawayama, Haruki Imaoka, +10

PLoS ONE

AsthmaInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +23

Validation of "Lung Age" Measured by Spirometry and Handy Electronic FEV1/FEV6 Meter in Pulmonary Diseases

Reiko Toda, Tomoaki Hoshino, Tomotaka Kawayama, +7

Internal Medicine

Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma

Hanako Oda, Tomotaka Kawayama, Haruki Imaoka, +11

Annals of Allergy Asthma & Immunology

AsthmaAllergyLung InflammationRespiratory DiseasesImmunology +7

Overexpression of Chitinase 3-Like 1/YKL-40 in Lung-Specific IL-18-Transgenic Mice, Smokers and COPD

Yuki Sakazaki, Tomoaki Hoshino, Satoko Takei, +12

PLoS ONE

Overexpression of IL-38 protein in anticancer drug-induced lung injury and acute exacerbation of idiopathic pulmonary fibrosis

Masaki Tominaga, Masaki Okamoto, Tomotaka Kawayama, +7

Respiratory Investigation

Acute Lung InjuryInflammationFibrosisAntifibrotic TherapyInflammatory Lung Disease +13

Effects of thioredoxin on established airway remodeling in a chronic antigen exposure asthma model

Haruki Imaoka, Tomoaki Hoshino, Satoko Takei, +8

Biochemical and Biophysical Research Communications

AsthmaInflammationAllergyInflammatory Lung DiseaseMedicine +6

Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis

Satoko Takei, Tomoaki Hoshino, Kazuko Matsunaga, +10

Arthritis Research & Therapy

Endogenous and Exogenous Thioredoxin 1 Prevents Goblet Cell Hyperplasia in a Chronic Antigen Exposure Asthma Model

Haruki Imaoka, Tomoaki Hoshino, Masaki Okamoto, +7

Allergology International