Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice

Hanh K. Le, Laura Graham, Esther Cha, +3

International Immunopharmacology

T CellsImmunologyImmune Checkpoint InhibitorTumor SuppressorBalb/c Mice +5

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

Johanna K. Morales, Maciej Kmieciak, Keith L. Knutson, +2

Breast Cancer Research and Treatment

Tumor BiologyBreast OncologyMedicineImmunologyMyeloid-derived Suppressor Cells +7

Essential roles of sphingosine-1–phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema

Carole A. Oskeritzian, Megan M. Price, Nitai C. Hait, +6

The Journal of Experimental Medicine

Cutting Edge: Mast Cells Critically Augment Myeloid-Derived Suppressor Cell Activity

Sheinei Saleem, Rebecca Martin, Johanna K. Morales, +7

The Journal of Immunology

Mast Cell DisorderInnate Immune SystemImmunologyImmunologic MechanismInnate Immunity +17

Radiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis

Mehran Habibi, Maciej Kmieciak, Laura Graham, +3

Breast Cancer Research and Treatment

Breast OncologyCancer ImmunosurveillanceRadiofrequency Thermal AblationMedicineImmunology +7

Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells

Johanna K. Morales, Maciej Kmieciak, Laura Graham, +3

Cancer Immunology Immunotherapy

Cell TherapyCancer ImmunosurveillanceGamma Chain CytokinesT-regulatory CellImmunology +7

IL-4 and TGF-β1 Counterbalance One Another while Regulating Mast Cell Homeostasis

Matthew Macey, Jamie Sturgill, Johanna K. Morales, +13

The Journal of Immunology

Mast Cell DisorderT-regulatory CellImmune RegulationImmunologyImmune System +16

The Fyn-STAT5 Pathway: A New Frontier in IgE- and IgG-Mediated Mast Cell Signaling

Yves T. Falanga, Johanna K. Morales, John Ryan

Frontiers in Immunology

Mast Cell DisorderImmunologyImmune RegulationNew FrontierImmunologic Mechanism +28

Myeloid-derived suppressor cells enhance IgE-mediated mast cell responses

Johanna K. Morales, Sheinei Saleem, Rebecca Martin, +13

Journal of Leukocyte Biology

Danger signals and nonself entity of tumor antigen are both required for eliciting effective immune responses against HER-2/neu positive mammary carcinoma: implications for vaccine design

Maciej Kmieciak, Johanna K. Morales, Joshua Morales, +3

Cancer Immunology Immunotherapy

VaccinationImmune EvasionTumor ImmunologyBreast OncologyCancer Immunosurveillance +11