Alice Biosa

GTPase activity regulates kinase activity and cellular phenotypes of Parkinson's disease-associated LRRK2

Alice Biosa, Alžbeta Trančíková, Laura Civiero et al. · Human Molecular Genetics · 2012 · 149 citations · Full text

Gtpase Activity, Molecular Regulation, Molecular Biology +20

LRRK2 Affects Vesicle Trafficking, Neurotransmitter Extracellular Level and Membrane Receptor Localization

Rossana Migheli, Maria Grazia Del Giudice, Ylenia Spissu et al. · PLoS ONE · 2013 · 89 citations · Full text

Role of LRRK2 in the regulation of dopamine receptor trafficking

Mauro Rassu, Maria Grazia Del Giudice, Simona Sanna et al. · PLoS ONE · 2017 · 81 citations · Full text

Sporadic Parkinson, Neurotransmitter, Cellular Neurobiology +17

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A

Pilar Rivero-Ríos, María Romo-Lozano, Jesús Madero‐Pérez et al. · Journal of Biological Chemistry · 2019 · 77 citations · Full text

G2019s Variant, Signal Transduction, Alters Endolysosomal Trafficking +10

Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils

Isabella Russo, Alice Kaganovich, Jinhui Ding et al. · Neurobiology of Disease · 2019 · 73 citations · Full text

Inflammation, Neuroinflammation, Neurodegenerative Diseases +15