Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

Young Hoon Sung, Jong Min Kim, Hyun-Taek Kim, +9

Genome Research

Rna-guided EndonucleasesCell ModificationGuide RnaNatural SciencesGenetics +13

Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1

Muhammad Ali, Sushil Devkota, Jae-il Roh, +2

Biochemical and Biophysical Research Communications

MitophagyMolecular BiologyTert-mtor InteractionCancer BiologyTumor Biology +14

CRISPR-Cas9-mediated generation of obese and diabetic mouse models

Jae-il Roh, Junghoon Lee, Seong-Uk Park, +6

EXPERIMENTAL ANIMALS

Knockout MouseMetabolic SyndromeSystems BiologyDevelopmental BiologyFunctional Genomics +13

Hexokinase 2 is a molecular bridge linking telomerase and autophagy

Jae-il Roh, Yu-Jin Kim, Jahyun Oh, +5

PLoS ONE

MitophagyMolecular RegulationMolecular BiologyUpstream FactorsCell Autophagy +16

Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

Yaechan Song, Heeju Na, Seung Eon Lee, +13

Nature Communications

EXIT: Extrapolation and Interpolation-based Neural Controlled Differential Equations for Time-series Classification and Forecasting

Sheo Yon Jhin, Jaehoon Lee, Minju Jo, +5

Proceedings of the ACM Web Conference 2022

Artificial IntelligenceForecasting MethodologyEngineeringMachine LearningExplicit Interpolation +17

Real-time qRT-PCR assay for the detection of miRNAs using bi-directional extension sequences

Kyung Jin Kim, Jiwon Kwak, Jaehoon Lee, +1

Analytical Biochemistry

Functional GenomicsEngineeringMedicineComputational BiologyBi-directional Extension Sequences +11

Impaired AKT signaling and lung tumorigenesis by PIERCE1 ablation in KRAS-mutant non-small cell lung cancer

Jae-il Roh, Jaehoon Lee, Young-Hoon Sung, +12

Oncogene

Transgenic overexpression of p23 induces spontaneous hydronephrosis in mice

Jaehoon Lee, Hye Jin Kim, Jung Ah Moon, +9

International Journal of Experimental Pathology

InflammationKidney AbnormalitiesRenal FunctionDisease MechanismP23 Tg Mice +11