Jonathan Whittaker

How insulin engages its primary binding site on the insulin receptor

John G. Menting, Jonathan Whittaker, Mai B. Margetts et al. · Nature · 2013 · 420 citations · Full text

Signal Transduction, Biochemistry, G Protein-coupled Receptor +9

Insulin-Resistant Diabetes Due to a Point Mutation That Prevents Insulin Proreceptor Processing

Yasunao Yoshimasa, Susumu Seino, Jonathan Whittaker et al. · Science · 1988 · 257 citations

Genetics, Immunology, Insulin Signaling +22

Protective hinge in insulin opens to enable its receptor engagement

John G. Menting, Yanwu Yang, Shu Jin Chan et al. · Proceedings of the National Academy of Sciences · 2014 · 182 citations · Full text

A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum

Jian-Wen Chen, Thomas Ledet, Hans Ørskov et al. · American Journal of Physiology-Endocrinology and Metabolism · 2003 · 175 citations

Immunology, Pathology, Insulin Signaling +25

Higher-Resolution Structure of the Human Insulin Receptor Ectodomain: Multi-Modal Inclusion of the Insert Domain

Tristan I. Croll, Brian J. Smith, Mai B. Margetts et al. · Structure · 2016 · 150 citations · Full text

Molecular Physiology, Signal Transduction, G Protein-coupled Receptor +11