Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

Christine E. Brown, Darya Alizadeh, Renate Starr, +19

New England Journal of Medicine

Cell TherapyImmunologyImmune RegulationImmunotherapeuticsHigh-grade Gliomas +15

Phase 1 studies of central memory–derived CD19 CAR T–cell therapy following autologous HSCT in patients with B-cell NHL

Xiuli Wang, Leslie Popplewell, Jamie R. Wagner, +19

Blood

Locoregional delivery of IL-13Rα2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial

Christine E. Brown, Jonathan Hibbard, Darya Alizadeh, +27

Nature Medicine

CD19-directed CAR T-cell therapy for treatment of primary CNS lymphoma

Tanya Siddiqi, Xiuli Wang, M. Suzette Blanchard, +9

Blood Advances

Cell TherapyImmunologyImmune RegulationImmunodominancePrimary Cns Lymphoma +21

Magnetic Resonance Imaging Tracking of Ferumoxytol-Labeled Human Neural Stem Cells: Studies Leading to Clinical Use

Margarita Gutova, Joseph A. Frank, Massimo D’Apuzzo, +15

Stem Cells Translational Medicine

PSCA-CAR T cell therapy in metastatic castration-resistant prostate cancer: a phase 1 trial

Tanya B. Dorff, M. Suzette Blanchard, Lauren Adkins, +25

Nature Medicine

Chimeric Antigen ReceptorCar T CellsUrologyCancer ImmunosurveillanceGenitourinary Cancer +12

Bortezomib and thalidomide maintenance after stem cell transplantation for multiple myeloma: a PETHEMA/GEM trial

Laura Rosiñol, Albert Oriol, Ana Isabel Teruel, +18

Leukemia

Hematological MalignancyTransplantationMarrow TransplantationOncologyPethema/gem Trial +8

A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine, administered with tetrahydrouridine

Edward M. Newman, Robert J. Morgan, Shivaani Kummar, +10

Cancer Chemotherapy and Pharmacology

Nucleic Acid ChemistryMedicineOligonucleotidePharmacodynamic EvaluationPharmacotherapy +3

Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma

Margarita Gutova, Gregory M. Shackleford, Vazgen Khankaldyyan, +13

Gene Therapy

Neuro-oncologyNeuroregenerationEpendymaGliomaMedicine +11

Systemic Anti–PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid

Jana Portnow, Dongrui Wang, M. Suzette Blanchard, +12

JAMA Oncology