Synthesis of Chalcones with Anticancer Activities

Suvitha Syam, Siddig İbrahim Abdelwahab, Mohammed Al-Mamary, +1

Molecules

Involvement of NF-κB and Bcl2/Bax signaling pathways in the apoptosis of MCF7 cells induced by a xanthone compound Pyranocycloartobiloxanthone A

Syam Mohan, Siddig İbrahim Abdelwahab, Behnam Kamalıdehghan, +10

Phytomedicine

InflammationMedicineApoptosisCell DeathMcf7 Cells +6

The methanolic extract of Boesenbergia rotunda (L.) Mansf. and its major compound pinostrobin induces anti-ulcerogenic property in vivo: Possible involvement of indirect antioxidant action

Siddig İbrahim Abdelwahab, Syam Mohan, Mahmood Ameen Abdulla, +6

Journal of Ethnopharmacology

Indirect Antioxidant ActionBiochemistryMedicineLipid PeroxidationPhysiology +8

In vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A, a chalcone isolated from Boesenbergia rotunda (L.) (fingerroot)

N.M. Isa, Siddig İbrahim Abdelwahab, Syam Mohan, +8

Brazilian Journal of Medical and Biological Research

Medicinal ChemistryPolyphenolicsFood Bioactive CompoundChemoprevention StrategyBiochemistry +13

The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest

Suvitha Syam, Ahmad Bustamam Abdul, Mohd Aspollah Sukari, +3

Molecules

Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: Its activation coupled with G0/G1 phase cell cycle arrest

Syam Mohan, Ahmad Bustamam Abdul, Siddig İbrahim Abdelwahab, +6

Journal of Ethnopharmacology

Signal TransductionParp CleavageBiochemistryNatural SciencesApoptosis +9

An anti-inflammatory molecular mechanism of action of α-mangostin, the major xanthone from the pericarp of <i>Garcinia mangostana</i>: an <i>in silico</i>, <i>in vitro</i> and <i>in vivo</i> approach

Syam Mohan, Suvitha Syam, Siddig İbrahim Abdelwahab, +1

Food & Function

ImmunologyPathologyInnate ImmunityOxidative StressInflammation +15

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-<i>κ</i>B Inhibition

Ismail Adam Arbab, Chung Yeng Looi, Ahmad Bustamam Abdul, +11

Evidence-based Complementary and Alternative Medicine

Chemoprevention StrategyApoptosisCell DeathProstate Cancer CellsCancer Biology +15

Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells

Siddig İbrahim Abdelwahab, Ahmad Bustamam Abdul, Syam Mohan, +4

Leukemia Research

Hematological MalignancyZerumbone Induces ApoptosisApoptosisHematologyCell Death +3

Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cells through the intrinsic pathway with involvement of NF-κB signalling and G0/G1 cell cycle arrest: A bioassay-guided approach

Ismail Adam Arbab, Ahmad Bustamam Abdul, Mohd Aspollah Sukari, +8

Journal of Ethnopharmacology

MedicineMcf-7 CellsApoptosisCycle ArrestOral Cavity +8