Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.

Joshua W Sokol, Joan Blanchette‐Mackie, Howard S. Kruth, +7

Journal of Biological Chemistry

PathologyHyperlipidemiaLipid MovementLysosomal AccumulationCellular Physiology +15

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes.

E. Joan Blanchette‐Mackie, Nancy K. Dwyer, L M Amende, +7

Proceedings of the National Academy of Sciences

PathologyCholesterol UtilizationCellular PhysiologyExcessive Cholesterol StorageDyslipidemia +15

Progesterone blocks cholesterol translocation from lysosomes.

J D Butler, Joan Blanchette‐Mackie, Ehud Goldin, +7

Journal of Biological Chemistry

Type C Niemann-Pick disease. Abnormal metabolism of low density lipoprotein in homozygous and heterozygous fibroblasts.

Howard S. Kruth, Marcella Comly, J D Butler, +5

Journal of Biological Chemistry

Metabolic DisorderPathologyFetal Bovine SerumHyperlipidemiaMetabolic Syndrome +15

A model of fulminant hepatic failure in the rabbit

Bennett L. Blitzer, Jeanne G. Waggoner, E. Anthony Jones, +9

Gastroenterology

Animal PhysiologyHepatologyLiver PhysiologyPhysiologyHistopathology +9

Type C Niemann-Pick disease. A parallel loss of regulatory responses in both the uptake and esterification of low density lipoprotein-derived cholesterol in cultured fibroblasts.

Peter G. Pentchev, Howard S. Kruth, Marcella Comly, +4

Journal of Biological Chemistry

PathologyHyperlipidemiaOxidative StressRegulatory ResponsesParallel Loss +16

Cysteamine depletes cystinotic leucocyte granular fractions of cystine by the mechanism of disulphide interchange

W. A. Gahl, Frank Tietze, J D Butler, +1

Biochemical Journal

Cysteine-cysteamine Mixed DisulphideBiochemistryAntiparasitic AgentMedicineNatural Sciences +10

Anti-inflammatory drugs in experimental atherosclerosis

J. Martyn Bailey, A.N. Makheja, J D Butler, +1

Atherosclerosis

InflammationAnti-inflammatoryCardiovascular DiseaseMedicineImmunology +7

Ascorbic acid accumulation and transport in human fibroblasts

Richard W. Welch, Peter Bergsten, J D Butler, +1

Biochemical Journal

Anti-inflammatory drugs in experimental atherosclerosis Part 1. Relative potencies for inhibiting plaque formation

J. Martyn Bailey, J D Butler

Atherosclerosis

InflammationThrombosisVascular DiseaseAnti-inflammatoryCardiovascular Disease +10