Marcella Comly

Niemann-Pick C1 Disease Gene: Homology to Mediators of Cholesterol Homeostasis

Eugene D. Carstea, Jill A. Morris, Katherine Coleman et al. · Science · 1997 · 1.5K citations

A defect in cholesterol esterification in Niemann-Pick disease (type C) patients.

Peter G. Pentchev, Marcella Comly, Howard S. Kruth et al. · Proceedings of the National Academy of Sciences · 1985 · 396 citations · Full text

Type C Niemann-Pick disease. Lysosomal accumulation and defective intracellular mobilization of low density lipoprotein cholesterol.

Joshua W Sokol, Joan Blanchette‐Mackie, Howard S. Kruth et al. · Journal of Biological Chemistry · 1988 · 233 citations · Full text

Pathology, Hyperlipidemia, Lipid Movement +17

Type-C Niemann-Pick disease: low density lipoprotein uptake is associated with premature cholesterol accumulation in the Golgi complex and excessive cholesterol storage in lysosomes.

E. Joan Blanchette‐Mackie, Nancy K. Dwyer, L M Amende et al. · Proceedings of the National Academy of Sciences · 1988 · 201 citations · Full text

Pathology, Cholesterol Utilization, Cellular Physiology +17

Group C Niemann‐Pick disease: faulty regulation of low‐density lipoprotein uptake and cholesterol storage in cultured fibroblasts

Peter G. Pentchev, Marcella Comly, Howard S. Kruth et al. · The FASEB Journal · 1987 · 197 citations

Pathology, Low‐density Lipoprotein, Hyperlipidemia +18