P. J. Ham

<i>In vitro</i>and<i>in vivo</i>profile of SB 206553, a potent 5‐HT_2C/5‐HT_2Breceptor antagonist with anxiolytic‐like properties

G.A. Kennett, Martyn Wood, Fiona Bright et al. · British Journal of Pharmacology · 1996 · 240 citations · Full text

Purification of an insect defensin from the mosquito, Aedes aegypti

R. Chalk, H. Townson, Shunji Natori et al. · Insect Biochemistry and Molecular Biology · 1994 · 85 citations

Biology, Insect Virus, Medicine +6

6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084):  The First Selective and Brain Penetrant 5-HT_2C Receptor Antagonist

Steven M. Bromidge, Malcolm Duckworth, Ian T. Forbes et al. · Journal of Medicinal Chemistry · 1997 · 84 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Chemical Biology +19

The Selective 5-HT_1BReceptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-<i>f</i>]indole-3,4‘-piperidine] (SB-224289) Potently Blocks Terminal 5-HT Autoreceptor Function Both in Vitro and in Vivo

Laramie M. Gaster, Frank E. Blaney, Susannah Davies et al. · Journal of Medicinal Chemistry · 1998 · 81 citations · Full text

Biarylcarbamoylindolines Are Novel and Selective 5-HT_2C Receptor Inverse Agonists:  Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a Potential Antidepressant/Anxiolytic Agent

Steven M. Bromidge, Steven Dabbs, David T. Davies et al. · Journal of Medicinal Chemistry · 2000 · 79 citations · Full text

Potential Antidepressant/anxiolytic Agent, Psychotropic Medication, Inverse Agonists +18