Specific inhibition of PAF-acether-induced platelet activation by BN 52021 and comparison with the PAF-acether inhibitors kadsurenone and CV 3988

Danièle Nunez, Michel Chignard, R. Korth, +5

European Journal of Pharmacology

ThrombopoiesisThrombosisMedicinal ChemistrySpecific InhibitionCardiovascular Disease +12

Preformed PAF‐acether and lyso PAF‐acether are bound to blood lipoproteins

Jacques Benveniste, Danièle Nunez, Patrick Duriez, +3

FEBS Letters

Human platelets release a paf‐acether: Acetylhydrolase similar to that in plasma

R. Korth, Jocelyne Bidualt, Rémi Palmantier, +2

Lipids

Comparison of three paf-acether receptor antagonist ginkgolides

R. Korth, Danièle Nunez, Jocelyne Bidault, +1

European Journal of Pharmacology

Medicinal ChemistryPharmacological StudyMedicinePharmacotherapyPharmacology +1

BN 52021 displaces [3H]paf-acether from, and inhibits its binding to intact human platelets

R. Korth, Jacques Benveniste

European Journal of Pharmacology

ThrombopoiesisThrombosisHuman PlateletsBlood PlateletMedicine +8

Lack of correlation between cytotoxicity of agonists and antagonists of platelet activating factor [paf-acether] in neoplastic cells and modulation of [3H]-paf-acether binding to platelets from humans in vitro.

Berdel We, R. Korth, Andreas S. Reichert, +6

PubMed

Chemoprevention StrategyImmunologyPharmacotherapyTumor BiologyInflammation +14

Interaction of the Paf antagonist WEB 2086 and its hetrazepine analogues with human platelets and endothelial cells

R. Korth, Masahiko Hirafuji, C. Lalau Keraly, +3

British Journal of Pharmacology

Endothelial CellsPharmacotherapyThrombosisMolecular PharmacologyHuman Platelets +16

Long time incubation of monocytic U 937 cells with LDL increases specific paf-acether binding and the cellular acetylhydrolase activity

R. Korth, Martin Middeke

Chemistry and Physics of Lipids

Protein FunctionSignal TransductionCellular EnzymologyBiochemistryCell Signaling +9

Unsaturated platelet-activating factor: Influence on aggregation, serotonin release and thromboxane synthesis of human thrombocytes

R. Korth, Hanno Riess, G. Brehm, +1

Thrombosis Research

InflammationThrombosisThrombopoiesisThromboxane SynthesisBlood Platelet +11

Lipoprotein-associated paf (LA-paf) was found in washed human platelets and monocyte/macrophage-like U937 cells

R. Korth, Klaus F. Zimmermann, Werner Richter

Chemistry and Physics of Lipids

InflammationLipoprotein-associated PafThrombopoiesisBlood PlateletHematology +7