Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

Keishi Makita, Kentaro Takahashi, Armando Karara, +3

Journal of Clinical Investigation

HypertensionRenal InflammationPharmacotherapyOxidative StressMolecular Pharmacology +21

Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties.

Armando Karara, Elizabeth Dishman, John R. Falck, +1

Journal of Biological Chemistry

Lipid AnalysisEndogenous Epoxyeicosatrienoyl-phospholipidsGlycobiologyFatty AcidsLipid Chemistry +14

Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.

Jorge H. Capdevila, Shouzuo Wei, Jun Yan, +5

Journal of Biological Chemistry

Lipid PeroxidationRenal InflammationRegulatory ControlRedox BiologyOxidative Stress +20

Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal arachidonic acid epoxygenase.

Jorge H. Capdevila, Armando Karara, David J. Waxman, +3

Journal of Biological Chemistry

Metabolomic ProfilingMicrosomal EpoxygenaseChemical BiologyRedox BiologyOxidative Stress +16

Arachidonic acid epoxygenase: Structural characterization and quantification of epoxyeicosatrienoates in plasma

Armando Karara, Shouzou Wei, D K Spady, +3

Biochemical and Biophysical Research Communications

Structural CharacterizationBiosynthesisAldehyde DehydrogenaseBiochemistryArachidonic Acid Epoxygenase +6

Endogenous epoxyeicosatrienoic acids

Armando Karara, Elizabeth Dishman, Ian A. Blair, +2

Journal of Biological Chemistry

Aldehyde DehydrogenaseBiochemistryMedicineLiver PhysiologyChiral Analysis +11

Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase

Armando Karara, Keishi Makita, H R Jacobson, +4

Journal of Biological Chemistry

[43] Cytochrome P-450 arachidonate oxygenase

Jorge H. Capdevila, John R. Falck, Elizabeth Dishman, +1

Methods in enzymology on CD-ROM/Methods in enzymology

Heme DegradationRedox BiologyBiochemistry

Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses

Kiyohiko Takahashi, Jorge H. Capdevila, Armando Karara, +3

American Journal of Physiology-Renal Physiology

Experimental PharmacologyRedox BiologyPharmacokineticsOxidative StressMolecular Pharmacology +16

Interleukin 1 alpha inhibits prostaglandin E2 release to suppress pulsatile release of luteinizing hormone but not follicle-stimulating hormone.

Valéria Rettori, M.F. Gimeno, Armando Karara, +2

Proceedings of the National Academy of Sciences

Human GrowthImmunologyE2 ReleaseSocial SciencesReproductive Endocrinology +21