PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments

Isabelle Tanjoni, Colin Walsh, Sean Uryu, +11

Cancer Biology & Therapy

Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models

Colin Walsh, Isabelle Tanjoni, Sean Uryu, +9

Cancer Biology & Therapy

Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells

Isabelle Tanjoni, Ricardo Weinlich, Maisa S. Della-Casa, +6

APOPTOSIS

InflammationAngiogenesisEndothelial CellsMedicineApoptosis +9

BnP1, a novel P-I metalloproteinase from Bothrops neuwiedi venom: Biological effects benchmarking relatively to jararhagin, a P-III SVMP

Cristiani Baldo, Isabelle Tanjoni, Ileana R. León, +11

Toxicon

P-iii SvmpBiological EffectsToxinologyNatural SciencesMedicine +8

Collagen binding is a key factor for the hemorrhagic activity of snake venom metalloproteinases

Ana M. Moura‐da‐Silva, Oscar Henrique Pereira Ramos, Cristiani Baldo, +11

Biochimie

InflammationMetalloproteinSnake Venom MetalloproteinasesVenomicsPathology +9

p190RhoGEF (Rgnef) Promotes Colon Carcinoma Tumor Progression via Interaction with Focal Adhesion Kinase

Honggang Yu, Ju‐Ock Nam, Nichol Miller, +8

Cancer Research

OncologySignal TransductionFocal Adhesion KinaseSignaling PathwayCell Signaling +11

Characterisation of local inflammatory response induced by Thalassophryne nattereri fish venom in a mouse model of tissue injury

Carla Lima, Patrı́cia Bianca Clissa, Ana Amélia Piran-Soares, +3

Toxicon

InflammationToxinologyPhysiologyImmunologyVenomics +9

Different regions of the class P-III snake venom metalloproteinase jararhagin are involved in binding to α2β1 integrin and collagen

Isabelle Tanjoni, Karla S. Evangelista, Maisa S. Della-Casa, +7

Toxicon

Snake venom metalloproteinases: structure/function relationships studies using monoclonal antibodies

Isabelle Tanjoni, Diego Butera, Luciana Bento, +6

Toxicon

ToxinologyMetalloproteinSnake Venom MetalloproteinasesImmunologyVenomics +3

Phylogenetic conservation of a snake venom metalloproteinase epitope recognized by a monoclonal antibody that neutralizes hemorrhagic activity

Isabelle Tanjoni, Diego Butera, Patrick Jack Spencer, +3

Toxicon

Phylogenetic ConservationImmunologyVenomicsPathologyHemorrhagic Activity +2