Mario Brufani

Synthesis of 2-Amino-5-sulfanyl-1,3,4-thiadiazole Derivatives and Evaluation of Their Antidepressant and Anxiolytic Activity

Francesca Clerici, Donato Pocar, Maddalena Guido et al. · Journal of Medicinal Chemistry · 2001 · 232 citations

Psychopharmacology, Organic Chemistry, Pharmacotherapy +20

“Back Door” Opening Implied by the Crystal Structure of a Carbamoylated Acetylcholinesterase

Cecilia Bartolucci, Emanuele Perola, Luciano Cellai et al. · Biochemistry · 1999 · 94 citations

Crystal Structure, Bioorganic Chemistry, Biochemistry +12

Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia

Mario Brufani, Maurizio Marta, Massimo Pomponi · European Journal of Biochemistry · 1986 · 78 citations · Full text

Long chain analogs of physostigmine as potential drugs for Alzheimer's disease: new insights into the mechanism of action in the inhibition of acetylcholinesterase

Emanuele Perola, Luciano Cellai, Doriano Lamba et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1997 · 60 citations

Inhibitory Activity, Potential Drugs, Alzheimer's Disease +13

4-Deoxypyrido[1',2':1,2]imidazo[5,4-c]rifamycin SV derivatives. A new series of semisynthetic rifamycins with high antibacterial activity and low gastroenteric absorption

Egidio Marchi, Giuseppe Mascellani, L. Montecchi et al. · Journal of Medicinal Chemistry · 1985 · 53 citations