Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma

Marta Larráyoz, María J. García‐Barchino, Jon Celay, +43

Nature Medicine

4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition

Nadine Nagy, Irina Gurevich, Hedwich F. Kuipers, +11

Journal of Biological Chemistry

Medicinal ChemistryMedicineGlycobiologyMechanism Of ActionMatrix Biology +4

The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice

Hedwich F. Kuipers, Nadine Nagy, Shannon M. Ruppert, +10

Clinical & Experimental Immunology

Pharmaceutical ScienceChemoprevention StrategyImmunologyPharmacotherapyBiomedical Engineering +16

Apoptosis-induced alkalinization by the Na⁺/H⁺ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729

Amy L. Grenier, Khaled Abu-ihweij, Ge Zhang, +7

American Journal of Physiology-Cell Physiology

Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance

John A. Gebe, Koshika Yadava, Shannon M. Ruppert, +17

American Journal of Respiratory Cell and Molecular Biology

AsthmaEnvironmental AllergyInflammatory Lung DiseaseLung InflammationAllergy Medicine +21

JunD/AP-1-Mediated Gene Expression Promotes Lymphocyte Growth Dependent on Interleukin-7 Signal Transduction

Shannon M. Ruppert, Mounir Chehtane, Ge Zhang, +3

PLoS ONE

ImmunologyImmune RegulationImmunologic MechanismInterleukin-7 Signal TransductionImmunotherapy +14

The Immune Response to Chronic <i>Pseudomonas aeruginosa</i> Wound Infection in Immunocompetent Mice

Johanna M. Sweere, Heather D. Ishak, Vivekananda Gupta Sunkari, +9

Advances in Wound Care

The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes

Shannon M. Ruppert, Wenqing Li, Ge Zhang, +4

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

InflammationCytokineMitophagyCell AutophagyAutoimmune Disease +12

Phase I Study of Safety and Pharmacokinetics of RO7297089, an Anti-BCMA/CD16a Bispecific Antibody, in Patients with Relapsed, Refractory Multiple Myeloma

Torben Plesner, Simon J. Harrison, Hang Quach, +15

Clinical Hematology International

Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways

Shannon M. Ruppert, Ben Falk, S. Alice Long, +1

International Journal of Cell Biology

T-regulatory CellApoptosisImmunologyImmune RegulationCell Death +15