Transcriptional Activation of the Human Glutathione Peroxidase Promoter by p53

Mingjia Tan, Shijun Li, Manju Swaroop, +3

Journal of Biological Chemistry

<i>PTGF-β</i> , a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway

Mingjia Tan, Yixin Wang, Kun‐Liang Guan, +1

Proceedings of the National Academy of Sciences

Cell ProliferationTumor BiologyP53 Target GenesCell RegulationGrowth Factor +15

A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells

Katrina Bockbrader, Mingjia Tan, Yi Sun

Oncogene

Breast OncologyMedicineApoptosisBreast Cancer CellsCell Death +6

APCCdc20 Suppresses Apoptosis through Targeting Bim for Ubiquitination and Destruction

Lixin Wan, Mingjia Tan, Jie Yang, +12

Developmental Cell

Cell RegulationApoptosisImmunologyCell DeathApccdc20 Suppresses Apoptosis +3

Ultraviolet Light Activates NFκB through Translational Inhibition of IκBα Synthesis

Shiyong Wu, Mingjia Tan, Yuanyuan Hu, +3

Journal of Biological Chemistry

Ultraviolet LightUv Light-induced ReductionMolecular BiologyCellular PhysiologyTumor Biology +15

FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4

Qiang Zhang, David Karnak, Mingjia Tan, +3

Molecular Cell

Structural BiologyMolecular BiologyFbxw7 Facilitates NonhomologousCross-link

Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells

Qiyin Zhou, Hua Li, Yuanyuan Li, +9

JCI Insight

Mitochondrial BiologyMetabolic RemodelingCancer BiologyTumor BiologyOxidative Stress +18

The FBXW2–MSX2–SOX2 axis regulates stem cell property and drug resistance of cancer cells

Yuan Yin, Chuan‐Ming Xie, Hua Li, +5

Proceedings of the National Academy of Sciences

SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation

Mingjia Tan, Yongchao Zhao, Sun Jung Kim, +5

Developmental Cell

Signal TransductionAngiogenesisDevelopmental BiologySignaling PathwayNeural Development +6

FBXW2 suppresses migration and invasion of lung cancer cells via promoting β-catenin ubiquitylation and degradation

Fei Yang, Jie Xu, Hua Li, +3

Nature Communications