Hiroshi Shigematsu

Inhibitory Regulation of Rac Activation, Membrane Ruffling, and Cell Migration by the G Protein-Coupled Sphingosine-1-Phosphate Receptor EDG5 but Not EDG1 or EDG3

Hiroyuki Okamoto, Noriko Takuwa, Takehiko Yokomizo et al. · Molecular and Cellular Biology · 2000 · 325 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

EDG1 Is a Functional Sphingosine-1-phosphate Receptor That Is Linked via a Gi/o to Multiple Signaling Pathways, Including Phospholipase C Activation, Ca2+Mobilization, Ras-Mitogen-activated Protein Kinase Activation, and Adenylate Cyclase Inhibition

Hiroyuki Okamoto, Noriko Takuwa, Koichi Gonda et al. · Journal of Biological Chemistry · 1998 · 285 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Long-Term Survival After Surgical Treatment of Patients With Takayasu’s Arteritis

Tetsuro Miyata, Osamu Sato, Hiroyuki Koyama et al. · Circulation · 2003 · 220 citations · Full text

Medicine, Surgery, Cardiothoracic Surgery +9

Randomized, double-blind, placebo-controlled clinical trial of hepatocyte growth factor plasmid for critical limb ischemia

Hiroshi Shigematsu, Kaoru Yasuda, Tomohiro Iwai et al. · Gene Therapy · 2010 · 213 citations

Medicine, Surgery, Hepatology +9

EDG3 Is a Functional Receptor Specific for Sphingosine 1-Phosphate and Sphingosylphosphorylcholine with Signaling Characteristics Distinct from EDG1 and AGR16

Hiroyuki Okamoto, Noriko Takuwa, Yutaka Yatomi et al. · Biochemical and Biophysical Research Communications · 1999 · 175 citations

Life Sciences, Biochemistry, Molecular Biology +14