Effects of PCSK9 Inhibition With Alirocumab on Lipoprotein Metabolism in Healthy Humans

Gissette Reyes‐Soffer, Marianna Pavlyha, Colleen Ngai, +19

Circulation

Lipoprotein lipase-mediated uptake and degradation of low density lipoproteins by fibroblasts and macrophages.

S C Rumsey, Joseph C. Obunike, Yadon Arad, +2

Journal of Clinical Investigation

InflammationLdl UptakeLipid SynthesisBiochemistryNatural Sciences +11

Mechanism of Increased LDL (Low-Density Lipoprotein) and Decreased Triglycerides With SGLT2 (Sodium-Glucose Cotransporter 2) Inhibition

Debapriya Basu, Lesley-Ann Huggins, Diego Scerbo, +6

Arteriosclerosis Thrombosis and Vascular Biology

Low-density LipoproteinHyperlipidemiaObesityMetabolic SyndromeAtherosclerosis +15

Lipoprotein lipase hydrolysis of retinyl ester. Possible implications for retinoid uptake by cells

William S. Blaner, Joseph C. Obunike, Sara Kurlandsky, +4

Journal of Biological Chemistry

Lipid PeroxidationRetinoid UptakeOxidative StressMetabolic SyndromePossible Implications +17

Subendothelial retention of lipoprotein (a). Evidence that reduced heparan sulfate promotes lipoprotein binding to subendothelial matrix.

Sivaram Pillarisetti, L Paka, Joseph C. Obunike, +2

Journal of Clinical Investigation

Tissue EngineeringVascular DiseaseEngineeringHeparan Sulfate PromotesBiomedical Engineering +20

Transcytosis of Lipoprotein Lipase across Cultured Endothelial Cells Requires Both Heparan Sulfate Proteoglycans and the Very Low Density Lipoprotein Receptor

Joseph C. Obunike, Erlo Lutz, Zhaohui Li, +6

Journal of Biological Chemistry

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

John S. Millar, Gissette Reyes‐Soffer, Patricia Jumes, +18

Journal of Clinical Investigation

Differentiated Macrophages Synthesize a Heparan Sulfate Proteoglycan and an Oversulfated Chondroitin Sulfate Proteoglycan That Bind Lipoprotein Lipase

Iris J. Edwards, Hongzhi Xu, Joseph C. Obunike, +2

Arteriosclerosis Thrombosis and Vascular Biology

Cellular differences in lipoprotein lipase-mediated uptake of low density lipoproteins.

Joseph C. Obunike, I J Edwards, S C Rumsey, +4

Journal of Biological Chemistry

Adipose-specific Lipoprotein Lipase Deficiency More Profoundly Affects Brown than White Fat Biology

Itsaso García‐Arcos, Yaeko Hiyama, Konstantinos Drosatos, +13

Journal of Biological Chemistry

Metabolic SyndromeWhite Fat BiologyBiochemistryLipid NutritionPhysiology +3