Brian R. de Costa

Neuronal localization of cannabinoid receptors in the basal ganglia of the rat

Miles Herkenham, Allison B. Lynn, Brian R. de Costa et al. · Brain Research · 1991 · 515 citations

Cannabis Use, Neurophysiology, Neuroanatomy +13

Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

Rae R. Matsumoto, Wayne D. Bowen, Michael A. Tom et al. · European Journal of Pharmacology · 1995 · 266 citations

Molecular Pharmacology, Antidystonic Effects, Medicine +8

Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain

Richard B. Rothman, Victor Bykov, Brian R. de Costa et al. · Peptides · 1990 · 146 citations

Opioid Epidemic, Neurophysiology, Addiction +14

Synthesis and evaluation of optically pure [³H]‐(+)‐pentazocine, a highly potent and selective radioligand for σ receptors

Brian R. de Costa, Wayne D. Bowen, Susan B. Hellewell et al. · FEBS Letters · 1989 · 141 citations · Full text

Pharmacotherapy, Heterocycle Chemistry, Experimental Pharmacology +16

Differential effects of systemically administered nor-binaltorphimine (nor-BNI) on κ-opioid agonists in the mouse writhing assay

Jillian H. Broadbear, S. Stevens Negus, Eduardo R. Butelman et al. · Psychopharmacology · 1994 · 138 citations

Molecular Pharmacology, Differential Effects, Behavioral Neuroscience +13