Victor Bykov

Interaction of endogenous opioid peptides and other drugs with four kappa opioid binding sites in guinea pig brain

Richard B. Rothman, Victor Bykov, Brian R. de Costa et al. · Peptides · 1990 · 146 citations

Opioid Epidemic, Neurophysiology, Addiction +14

beta-FNA binds irreversibly to the opiate receptor complex: in vivo and in vitro evidence.

Richard B. Rothman, Joseph B. Long, Victor Bykov et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 129 citations

Chronic administration of morphine and naltrexone up-regulate μ-opioid binding sites labeled by [3H][D-Ala2, MePhe4, Gly-ol5]enkephalin: further evidence for two μ-binding sites

Richard B. Rothman, Victor Bykov, Joseph B. Long et al. · European Journal of Pharmacology · 1989 · 84 citations

Opioid Epidemic, Molecular Pharmacology, Biochemistry +12

Upregulation of the opioid receptor complex by the chronic administration of morphine: A biochemical marker related to the development of tolerance and dependence

Richard B. Rothman, Joseph B. Long, Victor Bykov et al. · Peptides · 1991 · 61 citations

Opioid Epidemic, Pain Medicine, Chronic Administration +16

Chronic administration of morphine and naltrexone up-regulate[3H][d-ala2,d-leu5]enkephalin binding sites by different mechanisms

Janine A. Danks, Frank C. Tortella, Joseph B. Long et al. · Neuropharmacology · 1988 · 61 citations

Different Mechanisms, Signal Transduction, Functional Selectivity +9