Zhi-Cai Shi

Discovery and Characterization of Novel Tryptophan Hydroxylase Inhibitors That Selectively Inhibit Serotonin Synthesis in the Gastrointestinal Tract

Qingyun Liu, Qi Yang, Weimei Sun et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 153 citations

Modulation of Peripheral Serotonin Levels by Novel Tryptophan Hydroxylase Inhibitors for the Potential Treatment of Functional Gastrointestinal Disorders

Zhi-Cai Shi, Arokiasamy Devasagayaraj, Kunjian Gu et al. · Journal of Medicinal Chemistry · 2008 · 71 citations · Full text

Functional Gastrointestinal Disorders, Functional Gastrointestinal Disorder, Psychiatry +14

Substituted 3-(4-(1,3,5-triazin-2-yl)-phenyl)-2-aminopropanoic acids as novel tryptophan hydroxylase inhibitors

Haihong Jin, Giovanni Cianchetta, Arokiasamy Devasagayaraj et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 37 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +6

Mechanism of Inhibition of Novel Tryptophan Hydroxylase Inhibitors Revealed by Co-crystal Structures and Kinetic Analysis

Giovanni Cianchetta, Terry R. Stouch, Wangsheng Yu et al. · Current Chemical Genomics · 2010 · 34 citations · Full text

Tryptophan Complex, Drug Target, Aldo-keto Reductase +17

Discovery and characterization of potent small molecule inhibitors of the high affinity proline transporter

Xuan-Chuan Yu, Wandong Zhang, Arian Oldham et al. · Neuroscience Letters · 2009 · 22 citations

Drug Target, Biochemistry, Medicine +8