NCp7 Activates HIV-1Lai RNA Dimerization by Converting a Transient Loop-Loop Complex into a Stable Dimer

Delphine Muriaux, Hugues de Rocquigny, Bernard‐Pierre Roques, +1

Journal of Biological Chemistry

Structure-Based Dissection of the Active Site Chemistry of Leukotriene A4 Hydrolase: Implications for M1 Aminopeptidases and Inhibitor Design

Fredrik Tholander, A. Muroya, Bernard‐Pierre Roques, +3

Chemistry & Biology

Medicinal ChemistryBiochemistryLeukotriene A4 HydrolaseNatural SciencesEnzyme Catalysis +7

The Dual Peptidase Inhibitor RB101 Induces a Long‐Lasting Increase in the Extracellular Level of Met‐Enkephalin‐Like Material in the Nucleus Accumbens of Freely Moving Rats

Valérie Daugé, A. Mauborgne, François Cesselin, +2

Journal of Neurochemistry

Synaptic TransmissionNeurotransmitterNeurotransmissionFreely Moving RatsNucleus Accumbens +24

Joint quantum chemical and polarizable molecular mechanics investigation of formate complexes with penta- and hexahydrated Zn2+: Comparison between energetics of model bidentate, monodentate, and through-water Zn2+ binding modes and evaluation of nonadditivity effects

Gilles Tiraboschi, Bernard‐Pierre Roques, Nohad Gresh

Journal of Computational Chemistry

EngineeringComputational ChemistryChemistryWater MoleculesMolecular Simulation +17

Differential Interactions of the Growth Factor Receptor-bound Protein 2 N-SH3 Domain with Son of Sevenless and Dynamin

Michel Vidal, José Luis Montiel-Hernández, Didier Cussac, +6

Journal of Biological Chemistry

2,4-Dinitrophenyl 4-Methoxybenzyl Disulfide:  A New Efficient Reagent for the Electrophilic Sulfenylation of β-Amino Ester Enolates

Laurent Bischoff, Christelle David, L.O. Garcia Martin, +3

The Journal of Organic Chemistry

New Efficient ReagentMedicinal ChemistryBioorganic ChemistryEngineeringBiochemistry +13

A Model of PSI Dimerization:  Destabilization of the C²⁷⁸−G³⁰³Stem−Loop by the Nucleocapsid Protein (NCp10) of MoMuLV

Pierre‐Marie Girard, Hugues de Rocquigny, Bernard‐Pierre Roques, +1

Biochemistry

Biophysical ModelingSalt ConcentrationProtein AssemblyMolecular BiologyRna Dimerization +14

Thermolysin-inhibitor binding: Effect of the His231 → Ala mutation on the relative affinities of thiolate versus phosphoramidate inhibitors—a model theoretical investigation incorporating acontinuum reaction field hydration model

Nohad Gresh, Bernard‐Pierre Roques

Biopolymers

Representative Thiol InhibitorMolecular BiologyChemical BiologyEnzymatic ModificationMolecular Pharmacology +18

Intramolecular chelation of Zn²⁺ by α‐ and β‐mercaptocarboxamides. A parallel <i>ab initio</i> and polarizable molecular mechanics investigation. Assessment of the role of multipole transferability

Gilles Tiraboschi, Marie‐Claude Fournié‐Zaluski, Bernard‐Pierre Roques, +1

Journal of Computational Chemistry

EngineeringComputational ChemistryChemistryZn 2+Case Methanethiolate +14

N-[2-(Indan-1-yl)-3-mercapto-propionyl] amino acids as highly potent inhibitors of the three vasopeptidases (NEP, ACE, ECE): In vitro and In vivo activities

Nicolas Inguimbert, Hervé Poras, Franck Teffo, +7

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryVivo ActivitiesMedicineNatural Sciences +8