Concepedia

Author

Fredrik Tholander

Karolinska InstitutetORCID

Also Known As

F. Tholander, Fredrik Tholander

28

Publications

711

Citations

13

H-Index

24

Concepts

All Affiliations

Karolinska InstitutetLund UniversityStockholm UniversityPharmaleads (France)Département de Pharmacochimie Moléculaire
FT

About

Fredrik Tholander is an author at Karolinska Institutet specializing in biochemistry, natural sciences, and chemical biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Natural Sciences

5

5

237

2

Biochemistry

5

5

237

3

Medicine

3

3

60

4

Allergy

1

1

16

5

Cell Biology

1

1

16

Fredrik Tholander

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12

Publications

581

Citations

12

H-Index

YearCitations

VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients

Xiaojuan Yang, Yin Zhang, Kayoko Hosaka,

Proceedings of the National Academy of Sciences

2015

154

Structure-Based Dissection of the Active Site Chemistry of Leukotriene A4 Hydrolase: Implications for M1 Aminopeptidases and Inhibitor Design

Fredrik Tholander, A. Muroya, Bernard‐Pierre Roques,

Chemistry & Biology

2008

97

Leukotriene A4Hydrolase/Aminopeptidase

Peter Rudberg, Fredrik Tholander, Marjolein Thunnissen,

Journal of Biological Chemistry

2002

80

Leukotriene A4 Hydrolase

Peter Rudberg, Fredrik Tholander, Martina Andberg,

Journal of Biological Chemistry

2004

67

Leukotriene A <sub>4</sub> hydrolase: Selective abrogation of leukotriene B <sub>4</sub> formation by mutation of aspartic acid 375

Peter Rudberg, Fredrik Tholander, Marjolein Thunnissen,

Proceedings of the National Academy of Sciences

2002

46

Leukotriene A4 Hydrolase, Insights into the Molecular Evolution by Homology Modeling and Mutational Analysis of Enzyme from Saccharomyces cerevisiae

Fredrik Tholander, Filippa Kull, Eva Ohlson,

Journal of Biological Chemistry

2005

29

Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format

Fredrik Tholander, Britt‐Marie Sjöberg

Proceedings of the National Academy of Sciences

2012

27

A ribonucleotide reductase inhibitor with deoxyribonucleoside‐reversible cytotoxicity

Mikael Crona, Paula Codó, Venkateswara Rao Jonna,

Molecular Oncology

2016

21

Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology

Marcus J.G.W. Ladds, Gergana Popova, Andrés Pastor Fernández,

Journal of Biological Chemistry

2020

17

Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity

Shabbir Ahmad, A. Jimmy Ytterberg, Madhuranayaki Thulasingam,

Journal of Biological Chemistry

2016

16

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